Table 1: Urinary concentrations of mono-(2-ethyl-5-hydroxyhexyl)phthalate (MEHHP), mono-isobutyl phthalate (MIBP), and mono-benzyl phthalate (MBeP) to assess daily intakes of di(2-ethylhexyl)phthalate (DEHP), mono-butyl phthalate (MmBP), di-n-butyl phthalate (DNBP), di-isobutyl phthalate (DIBP), and benzylbutyl phthalate (BBP).
| |
Metabolite concentration
(µg/g creatinine) |
Phthalate intake
(µg/kg b.w.) |
Year of sampling |
Reference |
| Age, number |
Median |
95th
Percentile |
Max |
Median |
95th
Percentile |
Max |
| DEHP (EFSA TDI of 50 µg/kg bw/day) |
| USA |
| 6-11 y, n: 392
|
34.2
|
211
|
-
|
3.8
|
24
|
-
|
2001/02 |
NCEH 2005 |
| >20 y, n: 1638 |
15.0 |
134 |
- |
1.7 |
15 |
- |
| 6-9 y; n: 90 |
43.8 a |
- |
- |
5.0 |
- |
- |
2004/05 |
Wolff et al. 2007 |
| 6-10 y; n: 35 |
76.4 |
592 |
1101 |
8.7 |
67 |
125 |
2004 |
Teitelbaum et al. 2008 |
| Germany |
| 3-14 y, n: 254 |
39.9 |
170 |
1990 |
4.5 |
19 |
227 |
2001/02 |
Becker et al. 2004 |
| 2-7 y; n: 36
|
55.8
|
107
|
129
|
6.4
|
12
|
15
|
2003 |
Koch et al. 2004b |
| 20-59 y; n: 19 |
28.1 |
64 |
103 |
3.2 |
5.7 |
12 |
| DNBP (EFSA TDI of 10 µg/kg bw/day) |
| USA |
| 6-11 y, n = 392
|
35.1
|
146
|
-
|
1.3
|
5.3
|
-
|
2001/02 |
NCEH 2005 |
| >20 y, n: 1638 |
15.4 |
71.6 |
- |
0.6 |
2.6 |
- |
| 6-9 y; n: 90 |
44.1a |
- |
- |
|
- |
- |
2004/05 |
Wolff et al. 2007 |
| 6-10 y; n: 35 |
52.6 |
165.1 |
661 |
1.9 |
6.0 |
24.0 |
2004 |
Teitelbaum et al. 2008 |
| Germany |
| 2-14 y, n = 239 |
136 |
491 |
2102 |
4.9 |
17.8 |
76 |
2001/02 |
Koch et al 2007 |
| DIBP (no TDI allocated) |
| USA |
| 6-11 y, n: 392
|
5.2
|
24
|
-
|
0.2
|
0.9
|
-
|
2001/02 |
NCEH 2005 |
| >20 y, n: 1638 |
2.2 |
11 |
- |
0.1 |
0.4 |
- |
| 6-9 y; n: 90 |
11.1 |
- |
- |
0.4 |
- |
- |
2004/05 |
Wolff et al. 2007 |
| 6-10 y; n: 35 |
15.6 |
50.9 |
158 |
0.7 |
1.8 |
5.7 |
2004 |
Teitelbaum et al. 2008 |
| BBP (EFSA TDI of 500 µg/kg bw/day) |
| USA |
| 6-11 y, n = 392
|
37.2
|
195
|
-
|
1.2
|
6.5
|
-
|
2001/02 |
NCEH 2005 |
| >20 y, n: 1638 |
11.8 |
64.9 |
- |
0.4 |
2.2 |
- |
| 6-9 y; n: 90 |
28.7a |
- |
- |
1.0 |
- |
- |
2004/05 |
Wolff et al. 2007 |
| 6-10 y; n: 35 |
36.6 |
288 |
824 |
1.2 |
9.6 |
27.5 |
2004 |
Teitelbaum et al. 2008 |
| Germany |
| 2-14 y, n = 239 |
13.2 |
82.7 |
567 |
0.4 |
2.8 |
18.9 |
2001/02 |
Koch et al. 2007 |
*geometric mean
Source:
SCHER
Opinion on phthalates in school supplies (2008),
Section 3.4.1 “Exposure assessment”, pages 11-12.
Related publication: Other Figures & Tables on this publication: Table 1: Urinary concentrations of mono-(2-ethyl-5-hydroxyhexyl)phthalate (MEHHP), mono-isobutyl phthalate (MIBP), and mono-benzyl phthalate (MBeP) to assess daily intakes of di(2-ethylhexyl)phthalate (DEHP), mono-butyl phthalate (MmBP), di-n-butyl phthalate (DNBP), di-isobutyl phthalate (DIBP), and benzylbutyl phthalate (BBP). Some phthalates and their applications |
