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Table 3: Solubility of triclosan in selected solvents and chemicals

Solvent Solubility at 25°C
(g Triclosan/100 g solvent)
Distilled water (20°C) 0.001
Distilled water (50°C) 0.004
1 N caustic soda 31.7
1 N sodium carbonate 0.40
1 N ammonium hydroxide 0.30
Triethanolamine >100
Acetone >100
Ethanol 70% or 95% >100
Isopropanol >100
Propylene glycol >100
Polyethylene glycol >100
Methyl cellosolve (Union Carbide Corp.) >100
Ethyl cellosolve (Union Carbide Corp.) >100
Dipropylene glycol ~40
Glycerine 0.15
n-Hexane 8.5
Petroleum jelly (white, USP) ~0.5
Tween 20 (ICI America Inc.) >100
Tween 80 (ICI America Inc.) >100
Triton X-100 (Rohm & Haas) >100
Olive oil ~60
Castor oil ~90

Source: SCCS,  Opinion on triclosan (antimicrobial resistance) (2010) , p.10-12

Related publication:
Triclosan homeTriclosan and Antibiotics resistance
Other Figures & Tables on this publication:

Table 1: Purity specifications for triclosan since 1970

Table 2: Impurities in triclosan

Table 3: Solubility of triclosan in selected solvents and chemicals

Table 4: Environmental concentrations of triclosan

Table 5: Mechanisms of bacterial resistance to biocides at the cell level

Table 6: Bacterial mechanisms inducing potential cross-resistance