Table 11 Major resistance mechanisms (Davin-Regli et al. 2008)
|
Mechanism
|
Mechanical barrier
|
Enzymatic barrier
|
Target protection barrier
|
|
Type of activity
|
Influx
|
Efflux, active expel
|
Cleavage
|
Alteration
|
Target mutation
|
Protective molecule, new molecules
|
|
Susceptible antibiotic
|
ß-lactam, Quinolone etc.
|
ß-lactam, Aminoside etc.
|
ß-lactam
|
Phenicol, aminoside etc.
|
Quinolone, MLS etc.
|
ß-lactams, quinolone
|
Source: SCENIHR, 
Assessment of the Antibiotic Resistance Effects of Biocides (2009),
Section 3.5.1Resistance mechanisms to antibiotics, p. 41
Related publication:
Other Figures & Tables on this publication:
List of active molecules in biocidal products classified on the basis of chemical groups.
Table 2 List of active substances in biocidal products and their mode of action
Table 3 Biocides approved by US-FDA for health care settings, or registered by the US-EPA
Table 4 Commonly used skin disinfectants and antiseptics
Table 5 Major biocides used in veterinary medicine and animal husbandry
Table 6 Components of (udder) teat dips used (or having been used) in dairy animals
Table 7 Methodologies to measure bacterial resistance
Table 8 Bacterial mechanisms of resistance to biocides
Table 9 Bacteria isolated from contaminated cosmetic products and their resistance to biocides (Flores et al. 1997)
Table 10 Mechanisms of action of antibiotics
Table 11 Major resistance mechanisms (Davin-Regli et al. 2008)
Table: 23 Biocidal products listed in Annex V of the Biocides Directive (98/8/EC)
